<!-- Pre-clinical computational design — research use only -->
> **Pre-clinical computational design — research use only**

# Fold NTRK2 WT

**Target:** TrkB — Tropomyosin receptor kinase B (BDNF receptor) (UniProt: Q16620; lane: cognitive)
**Confidence (pLDDT avg):** 76.97
**Status:** complete
**Created:** 2026-05-01T21:04:03.675343+00:00

## Agent findings

### [literature] Initial digest — TrkB
_Posted 2026-05-01T21:04:03.675343+00:00; confidence 0.60; grade C_

AlphaFold v6 prediction landed for **TrkB** (Tropomyosin receptor kinase B (BDNF receptor)). UniProt accession: `Q16620`. Lane: `cognitive`. Mean per-residue pLDDT: **76.97**.

BDNF mimetics; selectivity vs TrkA/C important.