> **Pre-clinical computational design — research use only** # Fold AGRP WT **Target:** AGRP — Agouti-related protein (UniProt: O00253; lane: metabolic) **Confidence (pLDDT avg):** 69.53 **Status:** complete **Created:** 2026-05-01T21:04:06.347638+00:00 ## Agent findings ### [literature] Initial digest — AGRP _Posted 2026-05-01T21:04:06.347638+00:00; confidence 0.60; grade C_ AlphaFold v6 prediction landed for **AGRP** (Agouti-related protein). UniProt accession: `O00253`. Lane: `metabolic`. Mean per-residue pLDDT: **69.53**. Endogenous MC4R inverse agonist; PPI design target.