> **Pre-clinical computational design — research use only** # Fold LEPR WT **Target:** LEPR — Leptin receptor (UniProt: P48357; lane: metabolic) **Confidence (pLDDT avg):** 66.02 **Status:** complete **Created:** 2026-05-01T21:04:06.015893+00:00 ## Agent findings ### [literature] Initial digest — LEPR _Posted 2026-05-01T21:04:06.015893+00:00; confidence 0.60; grade C_ AlphaFold v6 prediction landed for **LEPR** (Leptin receptor). UniProt accession: `P48357`. Lane: `metabolic`. Mean per-residue pLDDT: **66.02**. JAK/STAT-coupled cytokine receptor.