> **Pre-clinical computational design — research use only** # Fold TLR4 WT **Target:** TLR4 — Toll-like receptor 4 (UniProt: O00206; lane: immune_resilience) **Confidence (pLDDT avg):** 89.20 **Status:** complete **Created:** 2026-05-01T21:04:14.374474+00:00 ## Agent findings ### [literature] Initial digest — TLR4 _Posted 2026-05-01T21:04:14.374474+00:00; confidence 0.60; grade C_ AlphaFold v6 prediction landed for **TLR4** (Toll-like receptor 4). UniProt accession: `O00206`. Lane: `immune_resilience`. Mean per-residue pLDDT: **89.2**. Agonist (adjuvant) and antagonist (sepsis) wedges both interesting.