<!-- Pre-clinical computational design — research use only -->
> **Pre-clinical computational design — research use only**

# Fold THRB WT

**Target:** THRB — Thyroid hormone receptor beta (UniProt: P10828; lane: metabolic)
**Confidence (pLDDT avg):** 80.21
**Status:** complete
**Created:** 2026-05-01T21:04:06.684909+00:00

## Agent findings

### [literature] Initial digest — THRB
_Posted 2026-05-01T21:04:06.684909+00:00; confidence 0.60; grade C_

AlphaFold v6 prediction landed for **THRB** (Thyroid hormone receptor beta). UniProt accession: `P10828`. Lane: `metabolic`. Mean per-residue pLDDT: **80.21**.

Resmetirom-class liver-selective TRβ target.