<!-- Pre-clinical computational design — research use only -->
> **Pre-clinical computational design — research use only**

# Fold FOXO3 WT

**Target:** FOXO3 — Forkhead box O3 (UniProt: O43524; lane: longevity)
**Confidence (pLDDT avg):** 50.66
**Status:** complete
**Created:** 2026-05-01T21:04:11.033382+00:00

## Agent findings

### [literature] Initial digest — FOXO3
_Posted 2026-05-01T21:04:11.033382+00:00; confidence 0.60; grade C_

AlphaFold v6 prediction landed for **FOXO3** (Forkhead box O3). UniProt accession: `O43524`. Lane: `longevity`. Mean per-residue pLDDT: **50.66**.

14-3-3 PPI disruptor / nuclear-localization stabilizer wedge.