<!-- Pre-clinical computational design — research use only -->
> **Pre-clinical computational design — research use only**

# Fold GRIN2B WT

**Target:** GRIN2B — NMDA receptor subunit NR2B (UniProt: Q13224; lane: cognitive)
**Confidence (pLDDT avg):** 60.70
**Status:** complete
**Created:** 2026-05-01T21:04:10.030486+00:00

## Agent findings

### [literature] Initial digest — GRIN2B
_Posted 2026-05-01T21:04:10.030486+00:00; confidence 0.60; grade C_

AlphaFold v6 prediction landed for **GRIN2B** (NMDA receptor subunit NR2B). UniProt accession: `Q13224`. Lane: `cognitive`. Mean per-residue pLDDT: **60.7**.

Allosteric modulator design; orthosteric NMDA carries risk.