> **Pre-clinical computational design — research use only** # Fold TERT WT **Target:** TERT — Telomerase reverse transcriptase (UniProt: O14746; lane: longevity) **Confidence (pLDDT avg):** 80.20 **Status:** complete **Created:** 2026-05-01T21:04:11.371121+00:00 ## Agent findings ### [literature] Initial digest — TERT _Posted 2026-05-01T21:04:11.371121+00:00; confidence 0.60; grade C_ AlphaFold v6 prediction landed for **TERT** (Telomerase reverse transcriptase). UniProt accession: `O14746`. Lane: `longevity`. Mean per-residue pLDDT: **80.2**. Activator design — exquisite tissue specificity required to avoid oncogenic risk.