> **Pre-clinical computational design — research use only** # Fold KL WT **Target:** Klotho-FGF23 — α-Klotho / FGF23 axis (UniProt: Q9UEF7; lane: longevity) **Confidence (pLDDT avg):** 89.09 **Status:** complete **Created:** 2026-05-01T21:04:04.005133+00:00 ## Agent findings ### [literature] Initial digest — Klotho-FGF23 _Posted 2026-05-01T21:04:04.005133+00:00; confidence 0.60; grade C_ AlphaFold v6 prediction landed for **Klotho-FGF23** (α-Klotho / FGF23 axis). UniProt accession: `Q9UEF7`. Lane: `longevity`. Mean per-residue pLDDT: **89.09**. Mimetics — peptide fragments shown to extend healthspan in mouse.