MTOR

Mechanistic target of rapamycin / UniProt P42345

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1

Mean pLDDT 77.97 Confident backbone model

Residues 2549 per-residue parsed

Coverage 100.0% 2549/2549 residues

Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

2549 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

2549 residues / mean 77.97 / min 23.27 / max 94.56

Very high 10.7% 272 residues / >=90

Confident 71.5% 1822 residues / 70-89

Low 8.0% 204 residues / 50-69

Very low 9.8% 251 residues / <50

Coverage

Near-complete coverage: 2549 observed of 2549 residues.

Low-confidence intervals

res 285-358 / mean 36.26 res 2423-2494 / mean 40.7 res 1811-1871 / mean 39.08 res 1219-1260 / mean 49.55

UniProt P42345 / open in AlphaFold DB

04 / Target context

Biological lane

longevity

Family

kinase

Pocket modes

allo

Indication tags

autophagy, longevity, muscle_protein_synthesis

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.

Fold stats

Gene	MTOR
Length	2549 aa
pLDDT mean	77.97
Confidence	77.97%
pLDDT source	alphafold db
Model state	Confident backbone model
Status	complete
Lane	longevity

Research-use only. Structure confidence is not biological validation; it is a model-quality receipt for downstream evidence grading.

Markdown export Proof spine Learning loop

Proof spine

This fold has a Claim Graph receipt linking target context, AlphaFold metrics, candidate design state, evidence findings, and exports where those records exist.

How this could be wrong

computational-only status low-confidence AlphaFold regions missing functional-site annotations no candidate yet

Candidate peptides (0)

Sequences redacted under public scope.

No candidates designed for this fold yet.

Agent findings (1)

literature C 05-01 21:04

Initial digest — MTOR

AlphaFold v6 prediction landed for **MTOR** (Mechanistic target of rapamycin). UniProt accession: `P42345`. Lane: `longevity`. Mean per-residue pLDDT: **77.97**...