Peptide RX

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proof receipt / alphafold metric

AlphaFold metrics / THRB

Model-quality receipt for the fold. It is not biological validation.

grade B status metric-context receipt 3887ae10ade7 proof 33%

what this node claims

AlphaFold metrics / THRB

Model-quality receipt for the fold. It is not biological validation.

evidence / risk instrument

53%
thin proof
structure evidence gates risk export lineage 53
low debt pressure 21%
80%structurestrong
pLDDT 80.21
78%evidenceusable
grade B
0%gatesdebt
0/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
33%lineagedebt
incomplete spine

proof completeness

33% missing target, candidate, finding, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

confidence band
confident
confidence pct
80.21
coverage context
missing or not linked
interpretation
usable fold context with explicit model-confidence limits
pae context
missing or not linked
plddt avg
80.21
sequence length
0

AlphaFold metrics visual

Confident backbone model

80.2

461 residues / min 19.47 / max 98.81 / source alphafold db

PAE matrix for linked target
Very high 69.2% 319 residues / >=90
Confident 7.6% 35 residues / 70-89
Low 2.0% 9 residues / 50-69
Very low 21.3% 98 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 461 of 461 residues.

  • residues 1-95 / mean 28.28
  • residues 254-262 / mean 51.51
  • residues 207-209 / mean 64.66
proof debt register

Visible limits, not hidden cleanup.

21%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

medium missing PAE/context where AlphaFold DB is not linked attach pLDDT series, PAE matrix, or coverage evidence
low computational-only status add independent evidence, challenge result, or witness review before strengthening
medium no candidate yet leave visible until a stronger public receipt resolves it

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
missing PAE/context where AlphaFold DB is not linked medium visible weakens attach pLDDT series, PAE matrix, or coverage evidence
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
no candidate yet medium visible weakens leave visible until a stronger public receipt resolves it

what supports it

measured by AlphaFold confidence context fold:c26a28a2-77b9-4698-b821-e63c0de5a126 -> alphafold_metric:c26a28a2-77b9-4698-b821-e63c0de5a126 measured_by / B / 0.802

what it supports

No downstream proof edge yet.

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.