Peptide RX

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proof receipt / finding

Initial digest — CAMP-LL37

AlphaFold v6 prediction landed for **CAMP-LL37** (Cathelicidin antimicrobial peptide (LL-37 precursor)). UniProt accession: `P49913`. Lane: `immune_resilience`. Mean per-residue pLDDT: **79.98**. LL-37 is the active 3...

grade C status literature receipt 031e3ae4c75a proof 33%

what this node claims

Initial digest — CAMP-LL37

AlphaFold v6 prediction landed for **CAMP-LL37** (Cathelicidin antimicrobial peptide (LL-37 precursor)). UniProt accession: `P49913`. Lane: `immune_resilience`. Mean per-residue pLDDT: **79.98**. LL-37 is the active 3...

evidence / risk instrument

39%
thin proof
structure evidence gates risk export lineage 39
low debt pressure 29%
28%structuredebt
pLDDT pending
55%evidencethin
grade C
0%gatesdebt
0/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
33%lineagedebt
incomplete spine

proof completeness

33% missing target, alphafold_metric, candidate, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

confidence
0.6
evidence refs
1

AlphaFold metrics visual

Confident backbone model

80.0

170 residues / min 38.31 / max 98.12 / source alphafold db

PAE matrix for linked target
Very high 42.9% 73 residues / >=90
Confident 27.6% 47 residues / 70-89
Low 27.6% 47 residues / 50-69
Very low 1.8% 3 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 170 of 170 residues.

  • residues 128-149 / mean 55.72
  • residues 1-10 / mean 55.6
  • residues 164-170 / mean 59.46
  • residues 23-29 / mean 65.12
proof debt register

Visible limits, not hidden cleanup.

29%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

high low evidence grade attach graded finding with source-linked evidence
low computational-only status add independent evidence, challenge result, or witness review before strengthening
medium no candidate yet leave visible until a stronger public receipt resolves it

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
low evidence grade high blocks weakens attach graded finding with source-linked evidence
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
no candidate yet medium visible weakens leave visible until a stronger public receipt resolves it

what supports it

evidence finding attached fold:c7d803d2-6895-4c39-9c41-96fbbc324c9c -> finding:d53fccb9-728b-4091-bd17-823ae81a8f5d supports / C / 0.6

what it supports

No downstream proof edge yet.

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.