Peptide RX

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CXCR4

CXCR4 / Thymosin-β4 axis (TB-500) / UniProt P61073

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1
Mean pLDDT 82.26 Confident backbone model
Residues 352 per-residue parsed
Coverage 100.0% 352/352 residues
Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

352 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

PAE matrix for CXCR4-TMSB4-axis

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

352 residues / mean 82.26 / min 31.7 / max 98.5

Very high 57.4% 202 residues / >=90
Confident 21.6% 76 residues / 70-89
Low 8.2% 29 residues / 50-69
Very low 12.8% 45 residues / <50

Coverage

Near-complete coverage: 352 observed of 352 residues.

Low-confidence intervals

res 320-352 / mean 48.4 res 1-26 / mean 39.48 res 304-310 / mean 63.5 res 29-34 / mean 63.78

UniProt P61073 / open in AlphaFold DB

04 / Target context

Biological lane

recovery

Family

GPCR_class_A

Pocket modes

ortho, ppi

Indication tags

wound_healing, anti_inflammatory, regeneration

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.