Peptide RX

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GLP1R

Glucagon-like peptide-1 receptor / UniProt P43220

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1
Mean pLDDT 81.51 Confident backbone model
Residues 463 per-residue parsed
Coverage 100.0% 463/463 residues
Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

463 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

PAE matrix for GLP-1R

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

463 residues / mean 81.51 / min 27.03 / max 98.25

Very high 47.1% 218 residues / >=90
Confident 35.6% 165 residues / 70-89
Low 5.8% 27 residues / 50-69
Very low 11.4% 53 residues / <50

Coverage

Near-complete coverage: 463 observed of 463 residues.

Low-confidence intervals

res 432-463 / mean 43.36 res 1-30 / mean 39.91 res 130-137 / mean 55.76 res 370-376 / mean 59.89

UniProt P43220 / open in AlphaFold DB

04 / Target context

Biological lane

metabolic

Family

GPCR_class_B

Pocket modes

ortho, allo

Indication tags

obesity, type_2_diabetes, cardiovascular

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.