Peptide RX

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FOXO3

Forkhead box O3 / UniProt O43524

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1
Mean pLDDT 50.66 Low-confidence regions present
Residues 673 per-residue parsed
Coverage 100.0% 673/673 residues
Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

673 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

PAE matrix for FOXO3

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

673 residues / mean 50.66 / min 30.38 / max 97.69

Very high 9.2% 62 residues / >=90
Confident 4.2% 28 residues / 70-89
Low 17.5% 118 residues / 50-69
Very low 69.1% 465 residues / <50

Coverage

Near-complete coverage: 673 observed of 673 residues.

Low-confidence intervals

res 240-622 / mean 43.05 res 1-153 / mean 47.37 res 630-673 / mean 45.99 res 201-202 / mean 64.41

UniProt O43524 / open in AlphaFold DB

04 / Target context

Biological lane

longevity

Family

transcription_factor

Pocket modes

ppi

Indication tags

longevity_genetics, stress_resistance

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.