Peptide RX

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CHRNA7

Alpha-7 nicotinic acetylcholine receptor / UniProt P36544

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1
Mean pLDDT 78.33 Confident backbone model
Residues 502 per-residue parsed
Coverage 100.0% 502/502 residues
Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

502 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

PAE matrix for CHRNA7

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

502 residues / mean 78.33 / min 28.12 / max 96.94

Very high 38.4% 193 residues / >=90
Confident 38.2% 192 residues / 70-89
Low 7.4% 37 residues / 50-69
Very low 15.9% 80 residues / <50

Coverage

Near-complete coverage: 502 observed of 502 residues.

Low-confidence intervals

res 346-430 / mean 37.37 res 1-21 / mean 57.58 res 322-325 / mean 68.91 res 500-502 / mean 62.88

UniProt P36544 / open in AlphaFold DB

04 / Target context

Biological lane

cognitive

Family

ligand_gated_ion_channel

Pocket modes

ortho, allo

Indication tags

attention, neuroprotection

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.