Initial digest — IGF1R receipt

what this node claims

Initial digest — IGF1R

AlphaFold v6 prediction landed for **IGF1R** (Insulin-like growth factor 1 receptor). UniProt accession: `P08069`. Lane: `recovery`. Mean per-residue pLDDT: **78.02**. Mecasermin axis.

Open source surface

vertical proof spine

evidence / risk instrument

39%

thin proof

low debt pressure 29%

28%structuredebt

pLDDT pending

55%evidencethin

grade C

0%gatesdebt

0/5 gates

100%riskstrong

0 hard flags

22%exportdebt

no export

33%lineagedebt

incomplete spine

proof completeness

33% missing target, alphafold_metric, candidate, export

01 target
02 fold
03 alphafold metric
04 candidate
05 finding
06 export

Metrics and receipt inputs

confidence: 0.6
evidence refs: 1

AlphaFold metrics visual

Confident backbone model

78.0

1367 residues / min 23.3 / max 98.0 / source alphafold db

Very high 43.6% 596 residues / >=90

Confident 31.6% 432 residues / 70-89

Low 9.1% 124 residues / 50-69

Very low 15.7% 215 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 1367 of 1367 residues.

residues 1286-1367 / mean 32.12
residues 723-774 / mean 39.62
residues 1-30 / mean 36.96
residues 675-704 / mean 38.91

proof debt register

Visible limits, not hidden cleanup.

29%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

high low evidence grade attach graded finding with source-linked evidence

low computational-only status add independent evidence, challenge result, or witness review before strengthening

medium no candidate yet leave visible until a stronger public receipt resolves it

Initial digest — IGF1R