Peptide RX

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proof receipt / finding

Initial digest — MTOR

AlphaFold v6 prediction landed for **MTOR** (Mechanistic target of rapamycin). UniProt accession: `P42345`. Lane: `longevity`. Mean per-residue pLDDT: **77.97**. Selective TORC1 inhibitor (rapalog-class) wedge — mTORC...

grade C status literature receipt bb304830ad4c proof 33%

what this node claims

Initial digest — MTOR

AlphaFold v6 prediction landed for **MTOR** (Mechanistic target of rapamycin). UniProt accession: `P42345`. Lane: `longevity`. Mean per-residue pLDDT: **77.97**. Selective TORC1 inhibitor (rapalog-class) wedge — mTORC...

evidence / risk instrument

39%
thin proof
structure evidence gates risk export lineage 39
low debt pressure 29%
28%structuredebt
pLDDT pending
55%evidencethin
grade C
0%gatesdebt
0/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
33%lineagedebt
incomplete spine

proof completeness

33% missing target, alphafold_metric, candidate, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

confidence
0.6
evidence refs
1

AlphaFold metrics visual

Confident backbone model

78.0

2549 residues / min 23.27 / max 94.56 / source alphafold db

PAE matrix for linked target
Very high 10.7% 272 residues / >=90
Confident 71.5% 1822 residues / 70-89
Low 8.0% 204 residues / 50-69
Very low 9.8% 251 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 2549 of 2549 residues.

  • residues 285-358 / mean 36.26
  • residues 2423-2494 / mean 40.7
  • residues 1811-1871 / mean 39.08
  • residues 1219-1260 / mean 49.55
proof debt register

Visible limits, not hidden cleanup.

29%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

high low evidence grade attach graded finding with source-linked evidence
low computational-only status add independent evidence, challenge result, or witness review before strengthening
medium no candidate yet leave visible until a stronger public receipt resolves it

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
low evidence grade high blocks weakens attach graded finding with source-linked evidence
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
no candidate yet medium visible weakens leave visible until a stronger public receipt resolves it

what supports it

evidence finding attached fold:63754d3c-0db9-433b-9610-6dd0157f9cb5 -> finding:6c8b0085-8bc2-4b39-872a-053988262db8 supports / C / 0.6

what it supports

No downstream proof edge yet.

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.