Initial digest — MC1R receipt

what this node claims

Initial digest — MC1R

AlphaFold v6 prediction landed for **MC1R** (Melanocortin-1 receptor). UniProt accession: `Q01726`. Lane: `sexual_wellbeing`. Mean per-residue pLDDT: **80.51**. Selectivity discriminator vs MC4R for PT-141-class pepti...

Open source surface

vertical proof spine

evidence / risk instrument

39%

thin proof

low debt pressure 29%

28%structuredebt

pLDDT pending

55%evidencethin

grade C

0%gatesdebt

0/5 gates

100%riskstrong

0 hard flags

22%exportdebt

no export

33%lineagedebt

incomplete spine

proof completeness

33% missing target, alphafold_metric, candidate, export

01 target
02 fold
03 alphafold metric
04 candidate
05 finding
06 export

Metrics and receipt inputs

confidence: 0.6
evidence refs: 1

AlphaFold metrics visual

Confident backbone model

80.5

317 residues / min 26.03 / max 98.38 / source alphafold db

Very high 35.0% 111 residues / >=90

Confident 47.0% 149 residues / 70-89

Low 7.3% 23 residues / 50-69

Very low 10.7% 34 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 317 of 317 residues.

residues 1-34 / mean 40.89
residues 226-244 / mean 54.93
residues 316-317 / mean 60.66
residues 300-301 / mean 67.91

proof debt register

Visible limits, not hidden cleanup.

29%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

high low evidence grade attach graded finding with source-linked evidence

low computational-only status add independent evidence, challenge result, or witness review before strengthening

medium no candidate yet leave visible until a stronger public receipt resolves it

Initial digest — MC1R