Peptide RX

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proof receipt / fold

TERT WT

Structure prediction with public confidence context.

grade B status complete receipt 5b40dc523f84 proof 67%

what this node claims

TERT WT

Structure prediction with public confidence context.

Open source surface

vertical proof spine

  1. 01 TERT WT fold / grade B / 64% 2 debt
  2. 02 AlphaFold metrics / TERT alphafold metric / grade B / 72% 1 debt
  3. 03 Initial digest — TERT finding / grade C / 47% 1 debt
  4. 04 fold.complete timeline event / grade C / 55%
  5. 05 TERT target / grade B / 70% 1 debt

evidence / risk instrument

50%
thin proof
structure evidence gates risk export lineage 50
visible debt pressure 47%
80%structurestrong
pLDDT 80.2
55%evidencethin
grade C
0%gatesdebt
0/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
67%lineageusable
incomplete spine

proof completeness

67% missing candidate, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

confidence band
confident
confidence pct
80.2
coverage available
false
gene
TERT
has structure
true
pae available
false
plddt avg
80.2
sequence length
0
variant
WT

AlphaFold metrics visual

Confident backbone model

80.2

1132 residues / min 21.31 / max 98.56 / source alphafold db

PAE matrix for linked target
Very high 58.3% 660 residues / >=90
Confident 21.1% 239 residues / 70-89
Low 3.9% 44 residues / 50-69
Very low 16.7% 189 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 1132 of 1132 residues.

  • residues 179-323 / mean 28.06
  • residues 417-443 / mean 38.37
  • residues 636-654 / mean 47.04
  • residues 367-380 / mean 46.25
proof debt register

Visible limits, not hidden cleanup.

47%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

low computational-only status add independent evidence, challenge result, or witness review before strengthening
medium no candidate yet leave visible until a stronger public receipt resolves it
medium missing PAE/context where AlphaFold DB is not linked attach pLDDT series, PAE matrix, or coverage evidence
high low evidence grade attach graded finding with source-linked evidence
medium missing functional-site annotations link target annotation, GO term, or binding-site context

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
no candidate yet medium visible weakens leave visible until a stronger public receipt resolves it
missing PAE/context where AlphaFold DB is not linked medium visible weakens attach pLDDT series, PAE matrix, or coverage evidence
low evidence grade high blocks weakens attach graded finding with source-linked evidence
missing functional-site annotations medium visible weakens link target annotation, GO term, or binding-site context

what supports it

target has structure prediction target:dcba88f5-3271-41fb-9e87-60505135534d -> fold:e7169022-fda3-45ba-a266-850753926013 folds_to / B / 0.802

what it supports

measured by AlphaFold confidence context fold:e7169022-fda3-45ba-a266-850753926013 -> alphafold_metric:e7169022-fda3-45ba-a266-850753926013 measured_by / B / 0.802
evidence finding attached fold:e7169022-fda3-45ba-a266-850753926013 -> finding:4f371dc5-9102-435b-ad6d-95161f7c964d supports / C / 0.6
timeline records state change fold:e7169022-fda3-45ba-a266-850753926013 -> timeline_event:31 records / C / 0.5

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.