Peptide RX

back to gallery / lane metabolic

AGRP

Agouti-related protein / UniProt O00253

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1
Mean pLDDT 69.53 Low-confidence regions present
Residues 132 per-residue parsed
Coverage 100.0% 132/132 residues
Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

132 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

PAE matrix for AGRP

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

132 residues / mean 69.53 / min 35.16 / max 96.06

Very high 21.2% 28 residues / >=90
Confident 29.5% 39 residues / 70-89
Low 27.3% 36 residues / 50-69
Very low 22.0% 29 residues / <50

Coverage

Near-complete coverage: 132 observed of 132 residues.

Low-confidence intervals

res 16-58 / mean 47.61 res 75-85 / mean 60.44 res 123-132 / mean 61.68 res 1-1 / mean 65.25

UniProt O00253 / open in AlphaFold DB

04 / Target context

Biological lane

metabolic

Family

endogenous_peptide

Pocket modes

ppi

Indication tags

appetite, MC4R_inverse_agonist

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.