Peptide RX

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KL

α-Klotho / FGF23 axis / UniProt Q9UEF7

Fold Report v1

Model confidence, target context, and design-readiness state.

This page binds the structure viewer to AlphaFold confidence data, agent findings, redacted candidate state, and non-clinical evidence limits so every fold is inspectable before it moves into a dossier.

Structure: alphafold-cdn pLDDT: alphafold db Coverage: 100.0% PAE: AlphaFold DB Candidates: 0 Findings: 1
Mean pLDDT 89.09 Confident backbone model
Residues 1012 per-residue parsed
Coverage 100.0% 1012/1012 residues
Evidence refs 1 agent-linked items

01 / Structure

AlphaFold v6 / streamed through the structure proxy / drag to rotate / scroll to zoom

02 / Per-residue confidence

1012 residues - very high (>90) confident (70-90) low (50-70) very low (<50)

03 / AlphaFold metrics

Reference prediction from the AlphaFold Protein Structure Database: predicted aligned error (PAE) plus per-position model confidence.

Predicted aligned error

PAE matrix for Klotho-FGF23

Blue regions imply stronger relative-position confidence. Red off-diagonal regions signal domain-orientation uncertainty.

Predicted lDDT per position

1012 residues / mean 89.09 / min 28.19 / max 98.81

Very high 72.9% 738 residues / >=90
Confident 17.5% 177 residues / 70-89
Low 4.1% 41 residues / 50-69
Very low 5.5% 56 residues / <50

Coverage

Near-complete coverage: 1012 observed of 1012 residues.

Low-confidence intervals

res 1-33 / mean 37.0 res 97-119 / mean 41.65 res 957-979 / mean 56.7 res 1007-1012 / mean 55.1

UniProt Q9UEF7 / open in AlphaFold DB

04 / Target context

Biological lane

longevity

Family

single_pass_TM

Pocket modes

ppi

Indication tags

aging, renal, cognition

Functional sites

Functional-site annotations are not cached for this target yet.

Binding partners

Binding-partner context is not cached for this target yet.

Gene ontology

GO terms are not cached for this target yet.

Residue-level functional sites, binding partners, and ontology tags are ready for ingestion but not cached for this fold yet.