Peptide RX

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proof receipt / alphafold metric

AlphaFold metrics / HTR1A

Model-quality receipt for the fold. It is not biological validation.

grade B status metric-context receipt 3a7db0fa2b2e proof 33%

what this node claims

AlphaFold metrics / HTR1A

Model-quality receipt for the fold. It is not biological validation.

evidence / risk instrument

53%
thin proof
structure evidence gates risk export lineage 53
low debt pressure 21%
78%structureusable
pLDDT 77.81
78%evidenceusable
grade B
0%gatesdebt
0/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
33%lineagedebt
incomplete spine

proof completeness

33% missing target, candidate, finding, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

confidence band
confident
confidence pct
77.81
coverage context
missing or not linked
interpretation
usable fold context with explicit model-confidence limits
pae context
missing or not linked
plddt avg
77.81
sequence length
0

AlphaFold metrics visual

Confident backbone model

77.8

422 residues / min 26.25 / max 98.31 / source alphafold db

PAE matrix for linked target
Very high 51.7% 218 residues / >=90
Confident 20.6% 87 residues / 70-89
Low 5.0% 21 residues / 50-69
Very low 22.7% 96 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 422 of 422 residues.

  • residues 236-322 / mean 38.61
  • residues 1-25 / mean 46.21
  • residues 418-422 / mean 54.76
proof debt register

Visible limits, not hidden cleanup.

21%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

medium missing PAE/context where AlphaFold DB is not linked attach pLDDT series, PAE matrix, or coverage evidence
low computational-only status add independent evidence, challenge result, or witness review before strengthening
medium no candidate yet leave visible until a stronger public receipt resolves it

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
missing PAE/context where AlphaFold DB is not linked medium visible weakens attach pLDDT series, PAE matrix, or coverage evidence
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
no candidate yet medium visible weakens leave visible until a stronger public receipt resolves it

what supports it

measured by AlphaFold confidence context fold:3e086785-6c66-4693-84f6-efcc2ade976f -> alphafold_metric:3e086785-6c66-4693-84f6-efcc2ade976f measured_by / B / 0.778

what it supports

No downstream proof edge yet.

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.