Peptide RX

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proof receipt / alphafold metric

AlphaFold metrics / HTR2A

Model-quality receipt for the fold. It is not biological validation.

grade B status metric-context receipt 3a11accb4595 proof 33%

what this node claims

AlphaFold metrics / HTR2A

Model-quality receipt for the fold. It is not biological validation.

evidence / risk instrument

52%
thin proof
structure evidence gates risk export lineage 52
low debt pressure 21%
74%structureusable
pLDDT 73.74
78%evidenceusable
grade B
0%gatesdebt
0/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
33%lineagedebt
incomplete spine

proof completeness

33% missing target, candidate, finding, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

confidence band
confident
confidence pct
73.74
coverage context
missing or not linked
interpretation
usable fold context with explicit model-confidence limits
pae context
missing or not linked
plddt avg
73.74
sequence length
0

AlphaFold metrics visual

Confident backbone model

73.7

471 residues / min 26.22 / max 98.62 / source alphafold db

PAE matrix for linked target
Very high 50.7% 239 residues / >=90
Confident 10.6% 50 residues / 70-89
Low 11.3% 53 residues / 50-69
Very low 27.4% 129 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 471 of 471 residues.

  • residues 1-72 / mean 39.17
  • residues 401-471 / mean 43.53
  • residues 278-310 / mean 47.07
  • residues 182-187 / mean 63.99
proof debt register

Visible limits, not hidden cleanup.

21%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

medium missing PAE/context where AlphaFold DB is not linked attach pLDDT series, PAE matrix, or coverage evidence
low computational-only status add independent evidence, challenge result, or witness review before strengthening
medium no candidate yet leave visible until a stronger public receipt resolves it

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
missing PAE/context where AlphaFold DB is not linked medium visible weakens attach pLDDT series, PAE matrix, or coverage evidence
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
no candidate yet medium visible weakens leave visible until a stronger public receipt resolves it

what supports it

measured by AlphaFold confidence context fold:7021e13f-876c-4639-a9fb-3ae71e1847b4 -> alphafold_metric:7021e13f-876c-4639-a9fb-3ae71e1847b4 measured_by / B / 0.737

what it supports

No downstream proof edge yet.

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.