Initial digest — HTR1A receipt

what this node claims

Initial digest — HTR1A

AlphaFold v6 prediction landed for **HTR1A** (Serotonin receptor 5-HT1A). UniProt accession: `P08908`. Lane: `cognitive`. Mean per-residue pLDDT: **77.81**. _(no notes)_

Open source surface

vertical proof spine

evidence / risk instrument

39%

thin proof

low debt pressure 29%

28%structuredebt

pLDDT pending

55%evidencethin

grade C

0%gatesdebt

0/5 gates

100%riskstrong

0 hard flags

22%exportdebt

no export

33%lineagedebt

incomplete spine

proof completeness

33% missing target, alphafold_metric, candidate, export

01 target
02 fold
03 alphafold metric
04 candidate
05 finding
06 export

Metrics and receipt inputs

confidence: 0.6
evidence refs: 1

AlphaFold metrics visual

Confident backbone model

77.8

422 residues / min 26.25 / max 98.31 / source alphafold db

Very high 51.7% 218 residues / >=90

Confident 20.6% 87 residues / 70-89

Low 5.0% 21 residues / 50-69

Very low 22.7% 96 residues / <50

usable fold context with explicit model-confidence limits

Near-complete coverage / observed 422 of 422 residues.

residues 236-322 / mean 38.61
residues 1-25 / mean 46.21
residues 418-422 / mean 54.76

proof debt register

Visible limits, not hidden cleanup.

29%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

high low evidence grade attach graded finding with source-linked evidence

low computational-only status add independent evidence, challenge result, or witness review before strengthening

medium no candidate yet leave visible until a stronger public receipt resolves it

Initial digest — HTR1A