Peptide RX

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proof receipt / idea

Effect design run

increase mitochondrial respiration in skeletal muscle

grade C status complete receipt 7a60876e1a3b proof 33%

what this node claims

Effect design run

increase mitochondrial respiration in skeletal muscle

Open source surface

vertical proof spine

  1. 01 Effect design run idea / grade C / 55%
  2. 02 PRX-GHSR-001 candidate / grade D / 36% 3 debt
  3. 03 PRX-GHSR-002 candidate / grade D / 36% 3 debt
  4. 04 GHSR1a target / grade B / 70% 1 debt

evidence / risk instrument

41%
thin proof
structure evidence gates risk export lineage 41
visible debt pressure 55%
28%structuredebt
pLDDT pending
34%evidencedebt
grade D
60%gatesusable
3/5 gates
100%riskstrong
0 hard flags
22%exportdebt
no export
33%lineagedebt
incomplete spine

proof completeness

33% missing fold, alphafold_metric, finding, export
  1. 01 target
  2. 02 fold
  3. 03 alphafold metric
  4. 04 candidate
  5. 05 finding
  6. 06 export

Metrics and receipt inputs

candidate count
2
matcher
platform_research
proof debt register

Visible limits, not hidden cleanup.

55%

Peptide RX keeps unresolved proof debt attached to the public receipt. Some debts should be resolved; redaction and research-use boundaries should stay visible.

low computational-only status add independent evidence, challenge result, or witness review before strengthening
high low evidence grade attach graded finding with source-linked evidence
low sequence redacted keep sequence redacted publicly; expose only through authorized records
low computational-only status add independent evidence, challenge result, or witness review before strengthening
high low evidence grade attach graded finding with source-linked evidence
low sequence redacted keep sequence redacted publicly; expose only through authorized records

weakness and challenge edges

What would stop this from becoming stronger.

debt severity export claim strength next proof needed
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
low evidence grade high blocks weakens attach graded finding with source-linked evidence
sequence redacted low visible watch keep sequence redacted publicly; expose only through authorized records
computational-only status low visible watch add independent evidence, challenge result, or witness review before strengthening
low evidence grade high blocks weakens attach graded finding with source-linked evidence
sequence redacted low visible watch keep sequence redacted publicly; expose only through authorized records
missing functional-site annotations medium visible weakens link target annotation, GO term, or binding-site context

what supports it

No upstream proof edge yet.

what it supports

effect run proposed candidate idea:effect-run:5b6e0a6a-49f2-46e5-a721-92bd1daa7fcd -> candidate:PRX-GHSR-001 proposes / C / 0.58
effect run proposed candidate idea:effect-run:5b6e0a6a-49f2-46e5-a721-92bd1daa7fcd -> candidate:PRX-GHSR-002 proposes / C / 0.58
effect run matched target idea:effect-run:5b6e0a6a-49f2-46e5-a721-92bd1daa7fcd -> target:eec1bc4d-2823-4f2e-978f-afd3ccc93a4c targets / C / 0.52

Research-use boundary

This receipt describes public computational research state. It does not expose raw candidate sequences and does not make a clinical claim.